P-5-P Pyridoxal Phosphate P5P (50 mg/ 100 tablets)

Supplementation with P-5-P, Pyridoxal-5'- Phosphate, may be useful for those unable to produce it efficiently from pyridoxine in the liver. P-5-P, the "activated" coenzyme form of B6 is extensively involved in the metabolism of amino acids, nucleic acids and lipids. In the 1950's, researchers found deficiencies of B6 apparently related to increased use of prescription drugs, as well as the use of artificial preservatives, additives and colorings in our food. Excessive alcohol use, protein intake or contraceptive use may indicate a greater need for vitamin B6.  Observations during clinical treatment of patients who need vitamin B-6 supplementation have shown that when P-5-P is indicated, it is 10 times more effective than pyridoxine HCl. Decreased plasma levels of P-5-P have been shown in the following conditions: Immunological Disorders, Renal Disorders, Atherosclerosis, Hepatic Biliary Disorders, Pregnancy/Lactation and Cancer. In addition, patients with cirrhosis show an increase in alkaline phosphatase and degradation of P-5-P. Intestinal absorption of P-5-P is decreased in patients with celiac disease. The following drugs have been reported to decrease plasma levels and increase metabolic requirements of P-5-P: Oral Contraceptives ,Hydrazines ,Cycloserine , L-Dopa  and Penicillamine . Supplementation with Pyridoxal-5’-Phosphate is indicated for patients with amino acid deficiencies and intestinal malabsorption as well as for patients with increased need for vitamin B-6 due to toxicity, infections or metabolic impairments. Since there are many causes for vitamin B-6 deficiency, patients who do not respond to vitamin B-6 supplementation with pyridoxine HCl may benefit from Pyridoxal-5'- Phosphate supplementation.

As part of a well-balanced diet that is low in saturated fat and cholesterol, Vitamin B6 may reduce the risk of vascular disease. B6 is also important for proper amino acid metabolism and neurological functions.   P-5-P, Pyridoxal-5'- Phosphate, does not require any conversion in the liver, and may be a preferable supplement form of this nutrient. B6 is an enzyme catalyst in many body functions including energy metabolism, neurotransmitter functions, and muscle growth and repair.

• Coenzyme Form of Vitamin B-6
• Reduce  Risk of Cardiovascular Disease
• Use of Presciption Drugs, Contraceptives May Cause Vitamin B Deficiencies

**daily value not established

Other Ingredients: Cellulose, magnesium stearate, stearic acid, cellulose & glycerine coating, silica.

Does not contain: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, starch, preservatives or artificial color.

Directions: Adults take one (1) tablet daily with food. For best utilization, take with food.

**These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

About Country Life® Vitamins

With few exceptions, vitamins cannot be manufactured or synthesized by the body. They must be supplemented through the diet or supplementation. Some vitamins must be converted into active or coenzyme forms by the body before they can be utilized. The lack of vitamins over a long period of time can result in serious deficiencies. Vitamin supplementation does not produce instant results, but rather a prolonged program is required for regeneration. Every day new proposed therapeutic roles for vitamins are being explored. At Country Life®, the latest research for each new application of vitamins is carefully studied. As the rationale for new combinations develop, Country Life® is committed to bringing you state-of-the-art supplements.