SAM-e has been clinically shown to have the following benefits: Longevity, Joint Strength, Liver Detoxification, Mood and Brain Function..
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SAM-e 200 (200 mg 60 tablets)

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Jarrow Formulas

SAM-e 200 (200 mg 60 tablets)

Jarrow Formulas® pharmaceutical grade, stabilized SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.



  • Longevity
  • Joint Strength
  • Liver Detoxification
  • Mood and Brain Function
  • <


Brain Metabolism

Contains More of the Active S,S Form

Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.

Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process.* Proper methylation through substances such as SAM-e positively influences longevity.*

SAM-e has been clinically shown to have the following benefits:

SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase),which are substances important for liver function.*

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*

SAM-e supports the production of healthy connective tissue through transulfuration.  In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.*

Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health care consultant. Full Potency 200 mg SAM-e is derived from 400 mg of SAM-e tosylate disulfate. For best results, use with Jarrow Formulas® JarroSilâÃ

By Sophie Leonard - Flag 
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Updated May. 29, 2018, about 1 year ago

UPC: 790011200161
Distributed or manufactured from Jarrow Formulas. See more Jarrow Formulas products.
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Questions and answers:

Asked on: June 8, 2013
Question: I just want to confirm that this product http:www.seacoast.comsam-e-200jarrow-formulas200-mg-60-tabletsp5157 does NOT contain Mannitol. There is no full image of the entire label, so I can't see what other ingredients are in this product. Thank you.

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1. Statements and claims on have not been evaluated by the FDA and are not intended to treat or diagnose any ailment or disease.

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