Working...
Double Strength SAM-e 400 contains only the highest quality Italian SAM-e available on the market.  This ensures the most potent SAM-e product with the highest percentage of the active S,S form per serving. S-Adenosyl Methionine (SAM-e) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system.  .

SAM-e 400, Double Strength (30 tablets)

Buy 3 - Get free delivery on whole order

Doctor's Best - Science Based Nutrition

SAM-e 400, Double Strength

Doctor's Best Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

  • Enhances Mood and Neural Function
  • Supports Liver Health and Detoxification
  • Promotes Joint Comfort and Mobility

Details about product

By Crystal Patterson - Flag 
Comments? Question?
Updated Nov. 18, 2011, about 14 years ago

SKU: DRB-00151
UPC: 753950001510
Distributed or manufactured from Doctor's Best. See more Doctor's Best products.
SAM-e (200 mg 60 tablets)
SAM-e (200 mg 60 tablets) Doctor's Best


 43.99 
Doctor's Best
SAM-e 400 (400 mg 30 tablets)
SAM-e 400 (400 mg 30 tablets) Jarrow Formulas


 37.45 
Jarrow Formulas
SAM-e 200 (200 mg 20 tablets)
SAM-e 200 (200 mg 20 tablets) Jarrow Formulas


 14.95 
Jarrow Formulas

Be the first to tell us your thoughts.Add your testimonial

Questions and answers:

Asked on: October 31, 2013
Question: Does this product contain Mannitol? I am looking for enteric Sam e without Mannitol in blister packs.
  • A: Yes this SAM-E supplement does contain mannitol. The majority of SAM-e supplements do contain mannitol however we do carry one that does not by Now Foods that is also enteric coated however it is not in the blister packs. You can take a look at it with the link below. http://www.seacoast.com/sam-e/now-foods/30-tablets-400-mg/p3675

Explore More Products

SAM-e (200 mg 60 tablets)
SAM-e (200 mg 60 tablets) Doctor's Best


 43.99 
Doctor's Best
Tocotrienols (50 mg 60 softgels)
Tocotrienols (50 mg  60  softgels) Doctor's Best


 13.45 
Doctor's Best

same doctors double methyl, donation s methionine italian, highest percentage receive groups
1. Statements and claims on Seacoast.com have not been evaluated by the FDA and are not intended to treat or diagnose any ailment or disease.

What interests you?

Blood Builder (90 tabs)* MegaFood

Aller-Response - Bio-Aligned Formula (180 tabs)* Source Naturals

MSM Topical Cream (4 oz ) Metabolic Response Modifiers

Happy Camper, 120 Veggie Caps Natural Balance

Fibrovera AHS (90 capsules)* Arthur Andrew Medical

Could Chelation Be The Answer To Defeating Autism?
Modified Citrus Pectin and Alginates are all-natural products that work in a very unique way to both chelate and eliminate heavy metals from the body.

Steel Libido for Women (75 softgels)* Irwin Naturals

Homocysteine Resist (60 capsules)* Life Extension

SoFresh Adult Flossing Toothbrush (Soft) OraMedix Inc.

Fresh Green Black Walnut Wormwood Complex (2 oz) NOW Foods

Skin Restoring Phytoceramides with Lipowheat (30 veggie liquid caps)* Life Extension

Mega Nutrient | Nature’s Way Alive Multivitamin
Alive Multi Vitamin from Nature's Way is the complete daily multivitamin containing the best ingredients from whole-food sources.

Biotivia | Transmax |Potent Resveratrol Supplements
Biotivia Transmax rated best resveratrol supplement by Men's Health Magazine. On Sale. Lowest Price. Too Low to be advertised. orders@seacoastvitamins.com contact us today!

Silicea 9C Boiron

BrainAid (60 tablets) NutriCology

Vipera berus 9C Boiron

PGX Daily | Benefits, Treatments & Side Effects
PGX is the new science of appetite control. The PGX program can be a comfortable way to improve eating habits for life.

Rescue Remedy 20ML Bach

MucoStop (48 caps)* EnzyMedica

Para Smart (90 caps) Microbial Cleanse (2 Part Program)* Renew Life

Garcinia Cambogia Extract 50% HCA (90 v-caps) Top Secret Nutrition

Best Serrapeptase (40,000 Units - 270 capsules) Doctor's Best

Ultra Jarro-Dophilus (60 capsules)* Jarrow Formulas

Lung Bronchial and Sinus Health (90 tabs)* Natural Factors

Vitamin D Standards Too Low
A worldwide increase to 2,000 IU of vitamin D daily (or higher for some groups) could reduce the incidence of a number of diseases, including multiple sclerosis, cancer, type-1 diabetes, metabolic syndrome, cardiovascular disease and tuberculosis.

Zyflamend | New Chapter Zyflamend Side Effects
Zyflamend Bonus Pack