Working...
Double Strength SAM-e 400 contains only the highest quality Italian SAM-e available on the market.  This ensures the most potent SAM-e product with the highest percentage of the active S,S form per serving. S-Adenosyl Methionine (SAM-e) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system.  .

SAM-e 400, Double Strength (30 tablets)

Buy 3 - Get free delivery on whole order

Doctor's Best - Science Based Nutrition

SAM-e 400, Double Strength

Doctor's Best Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

  • Enhances Mood and Neural Function
  • Supports Liver Health and Detoxification
  • Promotes Joint Comfort and Mobility

Details about product

By Crystal Patterson - Flag 
Comments? Question?
Updated Nov. 18, 2011, about 14 years ago

SKU: DRB-00151
UPC: 753950001510
Distributed or manufactured from Doctor's Best. See more Doctor's Best products.
SAM-e (200 mg 60 tablets)
SAM-e (200 mg 60 tablets) Doctor's Best


 43.99 
Doctor's Best
SAM-e 400 (400 mg 30 tablets)
SAM-e 400 (400 mg 30 tablets) Jarrow Formulas


 37.45 
Jarrow Formulas
SAM-e 200 (200 mg 20 tablets)
SAM-e 200 (200 mg 20 tablets) Jarrow Formulas


 14.95 
Jarrow Formulas

Be the first to tell us your thoughts.Add your testimonial

Questions and answers:

Asked on: October 31, 2013
Question: Does this product contain Mannitol? I am looking for enteric Sam e without Mannitol in blister packs.
  • A: Yes this SAM-E supplement does contain mannitol. The majority of SAM-e supplements do contain mannitol however we do carry one that does not by Now Foods that is also enteric coated however it is not in the blister packs. You can take a look at it with the link below. http://www.seacoast.com/sam-e/now-foods/30-tablets-400-mg/p3675

Explore More Products

SAM-e (200 mg 60 tablets)
SAM-e (200 mg 60 tablets) Doctor's Best


 43.99 
Doctor's Best
Tocotrienols (50 mg 60 softgels)
Tocotrienols (50 mg  60  softgels) Doctor's Best


 13.45 
Doctor's Best

same doctors double methyl, donation s methionine italian, highest percentage receive groups
1. Statements and claims on Seacoast.com have not been evaluated by the FDA and are not intended to treat or diagnose any ailment or disease.

What interests you?

PRID (18 g) Hylands

Organic Wheat Grass Powder (9 oz) NOW Foods

Life Extension Mix Tablets (315 tablets)* Life Extension

SoFresh Adult Flossing Toothbrush (Soft) OraMedix Inc.

ProOmega Junior (90 Soft Gels)* Nordic Naturals

Diet-Phen (814 mg 180 tabs)* Source Naturals

RevitalX & Detoxitech | 7 Day Nutritional Cleansing Program* Natural Factors

Wobenzym | Systemic Enzymes | Wobenzym N
Wobenzym N is the authentic systemic enzyme formula developed by Mucos Pharma in Germany and trusted by millions of people worldwide for over 40 years. Free Shipping on all Wobenzym orders with delivery inside the United States.

Best Curcumin C3 Complex (1000mg - 120 tablets) Doctor's Best

Best Acetyl L-Carnitine featuring Sigma Tau Carnitine (588 mg)(120 capsules) Doctor's Best

ORAC-Energy Greens (60 day 364 g) Paradise Herbs

Best Collagen Types 1 & 3 Powder (200 gr) Doctor's Best

Warrior Food Extreme Ultimate Protein Supplement - Economy Size (Vanilla 1000 g)* HealthForce Nutritionals

Para Smart (90 caps) Microbial Cleanse (2 Part Program)* Renew Life

Argentum nitricum 30X Boiron

Best Fucoidan 70% Brown Seaweed (60 vegi capsules) Doctor's Best

Borage Oil (60 soft gels) Barleans Organic Oils

Blood Builder (90 tabs)* MegaFood

Mega Nutrient | Nature’s Way Alive Multivitamin
Alive Multi Vitamin from Nature's Way is the complete daily multivitamin containing the best ingredients from whole-food sources.

Sambucol Cold & Flu Fighter
Sambucol. World renowned original formula, clinically tested, virologist developed. Boost immunity. Unique black elderberry extract rich in immune supporting flavonoids. Cold & Flu Season Special.

GSE Grapefruit Seed Extract Defense Plus (90 Tabs) NutriBiotic

Sleep Tonight (28 Tabs) Enzymatic Therapy

Glycotrol (Diabetes) (180 capsules)* Lidtke

IP6 Inositol Called a Natural Cancer Fighter
IP6 Inositol Hexaphosphate has been called a "natural cancer fighter" and scientific studies suggest that it slows or reverses the growth of various forms of cancer, including breast, colon, and prostate cancers.

Graviola Tincture Certified Organic (2 oz.) Amazon Therapeutic Laboratories

Phenocane Curcumin (120 capsules) OxyLife